FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study.

@article{Schouten2009FGF23EA,
  title={FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study.},
  author={Belinda J Schouten and Penelope J Hunt and John Hamilton Livesey and Chris Frampton and Steven G Soule},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2009},
  volume={94 7},
  pages={
          2332-7
        }
}
CONTEXT Parenteral iron administration has been associated with hypophosphatemia. Fibroblast growth factor 23 (FGF23) has a physiological role in phosphate homeostasis via suppression of 25-hydroxyvitamin D [25(OH)D] activation and promotion of phosphaturia. We recently reported a case of iron-induced hypophosphatemic osteomalacia associated with marked FGF23 elevation. OBJECTIVE Our objective was to prospectively investigate the effect of parenteral iron polymaltose on phosphate homeostasis… CONTINUE READING

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