FGF18 as a prognostic and therapeutic biomarker in ovarian cancer.

  title={FGF18 as a prognostic and therapeutic biomarker in ovarian cancer.},
  author={Wei Wei and S. C. Mok and Esther A Oliva and Sung-Hoon Kim and Gayatry Mohapatra and Michael J. Birrer},
  journal={The Journal of clinical investigation},
  volume={123 10},
High-throughput genomic technologies have identified biomarkers and potential therapeutic targets for ovarian cancer. Comprehensive functional validation studies of the biological and clinical implications of these biomarkers are needed to advance them toward clinical use. Amplification of chromosomal region 5q31-5q35.3 has been used to predict poor prognosis in patients with advanced stage, high-grade serous ovarian cancer. In this study, we further dissected this large amplicon and identified… CONTINUE READING
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