FGF signaling interact to pattern mesoderm by controlling basic helix-1 loop-helix transcription factor activity 2 3

@inproceedings{Row2018FGFSI,
  title={FGF signaling interact to pattern mesoderm by controlling basic helix-1 loop-helix transcription factor activity 2 3},
  author={R. W. Harold Row and Amy Pegg and Brian A Kinney and Gist H. Farr and Lisa Maves and Sally Lowell and Valerie Wilson and Benjamin L. Martin},
  year={2018}
}
33 The mesodermal germ layer is patterned into mediolateral subtypes by signaling 34 factors including BMP and FGF. How these pathways are integrated to induce specific 35 mediolateral cell fates is not well understood. We used mesoderm derived from post36 gastrulation neuromesodermal progenitors (NMPs), which undergo a binary mediolateral 37 patterning decision, as a simplified model to understand how FGF acts together with 38 BMP to impart mediolateral fate. Using zebrafish and mouse NMPs, we… CONTINUE READING

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