FGF signaling in craniofacial biological control and pathological craniofacial development.

@article{Hatch2010FGFSI,
  title={FGF signaling in craniofacial biological control and pathological craniofacial development.},
  author={Nan E. Hatch},
  journal={Critical reviews in eukaryotic gene expression},
  year={2010},
  volume={20 4},
  pages={295-311}
}
  • Nan E. Hatch
  • Published 2010 in Critical reviews in eukaryotic gene expression
Fibroblast growth factor receptors comprise a family of four evolutionarily conserved transmembrane proteins (FGFR1, FGFR2, FGFR3 and FGFR4) known to be critical for the normal development of multiple organ systems. In this review we will primarily focus upon the role of FGF/FGFR signaling as it influences the development of the craniofacial skeleton. Signaling by FGF receptors is regulated by the tissue-specific expression of FGFR isoforms, receptor subtype specific fibroblast growth factors… CONTINUE READING

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