FGF signaling facilitates postinjury recovery of mouse hematopoietic system.

Abstract

Previous studies have shown that fibroblast growth factor (FGF) signaling promotes hematopoietic stem and progenitor cell (HSPC) expansion in vitro. However, it is unknown whether FGF promotes HSPC expansion in vivo. Here we examined FGF receptor 1 (FGFR1) expression and investigated its in vivo function in HSPCs. Conditional knockout (CKO) of Fgfr1 did not… (More)
DOI: 10.1182/blood-2011-11-393991

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Cite this paper

@article{Zhao2012FGFSF, title={FGF signaling facilitates postinjury recovery of mouse hematopoietic system.}, author={Meng Zhao and Jason T. Ross and Tomer Itkin and John M. Perry and Aparna Venkatraman and Jeffrey S. Haug and Mark J. Hembree and Chuxia X Deng and Tsvee Lapidot and Xi He and Linheng Li}, journal={Blood}, year={2012}, volume={120 9}, pages={1831-42} }