FGF signaling: its role in bone development and human skeleton diseases.

@article{Su2008FGFSI,
  title={FGF signaling: its role in bone development and human skeleton diseases.},
  author={Nan Su and Xiaolan Du and Lin Chen},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2008},
  volume={13},
  pages={2842-65}
}
Fibroblast growth factors (FGFs)/Fibroblast growth factor receptors (FGFRs) signaling has recently been found to play very important roles in bone development and diseases. Missense mutations in several FGFs and FGFRs were found in human to cause a variety of congenital bone diseases including chondrodysplasia syndromes, craniosynostosis syndromes, and syndromes with dysregulated phosphate metabolism, etc. In addition to its role in bone development and genetic diseases, FGF signaling is also… CONTINUE READING

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