FGF-dependent midline-derived progenitor cells in hypothalamic infundibular development.

@article{Pearson2011FGFdependentMP,
  title={FGF-dependent midline-derived progenitor cells in hypothalamic infundibular development.},
  author={Caroline Pearson and Kyoji Ohyama and Liz Manning and Soheil Aghamohammadzadeh and Helen Sang and Marysia A Placzek},
  journal={Development},
  year={2011},
  volume={138 12},
  pages={2613-24}
}
The infundibulum links the nervous and endocrine systems, serving as a crucial integrating centre for body homeostasis. Here we describe that the chick infundibulum derives from two subsets of anterior ventral midline cells. One set remains at the ventral midline and forms the posterior-ventral infundibulum. A second set migrates laterally, forming a collar around the midline. We show that collar cells are composed of Fgf3(+) SOX3(+) proliferating progenitors, the induction of which is SHH… CONTINUE READING
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Fibroblast growth factor signalling in the developing neuroendocrine hypothalamus

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  • Front . Neuroendocrinol .
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