FGF and EGF are mitogens for immortalized neural progenitors.

  title={FGF and EGF are mitogens for immortalized neural progenitors.},
  author={D L Kitchens and Evan Yale Snyder and David I. Gottlieb},
  journal={Journal of neurobiology},
  volume={25 7},
Individual neural progenitors, derived from the external germinal layer of neonatal murine cerebellum, were previously immortalized by the retrovirus-mediated transduction of avian myc (v-myc). C17-2 is one of those clonal multipotent progenitor cell lines (Snyder et al., 1992, Cell 68: 33-51; Ryder et al., 1990, J. Neurobiol. 21:356-375). When transplanted into newborn mouse cerebellum (CB), the cells participate in normal CB development; they engraft in a cytoarchitecturally appropriate… CONTINUE READING
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