author={Jim Schr{\"o}der and Anja Thlikainen and Albert de la Chapelle},
The presence of fetal cells in the maternal circulation after delivery was investigated by examining interphase cells for fluorescent Y-bodies after staining with quinacrine mustard. Mothers were excluded if their own autosomos had regions of brilliant fluorescence that simulated Y-bodies. In a study of 24 primiparas, the sex of whose children was unknown to the observer, the method was found to be reliable: 34 of the 240,000 cells examined showed a presumptive Y-body, and only one of these… 

Fetal cells in the maternal blood

It was shown that a good mitotic response and good chromosome preparations could be obtained from as few as 6000 lymphocytes.

Massive Invasion of Fetal Lymphocytes into the Mothers Blood at Induced Abortion

The tentative interpretation is that the XY cells in the proband's blood emanated from a previous fetus that was legally aborted by curettage on the 10th week of an uneventful pregnancy and which the patient admitted to only after repeated questioning.

Fetal cells in the blood of pregnant mothers.

This was the status of research on fetal cells in maternal blood in August 1980 before the publication of the paper by Kirsch-Volders et al.

Fetal nucleated cells in maternal peripheral blood after delivery.

Fetal nucleated cells in maternal peripheral blood: frequency and relationship to gestational age

The present study suggests that fetal nucleated cells increase in maternal peripheral blood with advancing gestation, from less than 1 in 100,000ucleated cells in the first trimester to around 1 in 10,000 at term, much lower than those reported by cytological methods.

Isolating fetal cells in maternal circulation for prenatal diagnosis

Polymerase chain reaction (PCR) technology is considered appropriate to offer this technology as an alternative to conventional invasive and non‐invasive methods of prenatal cytogenetic diagnosis only upon completion of clinical evaluations.

Fetomaternal cell trafficking: a new cause of disease?

  • D. Bianchi
  • Medicine, Biology
    American journal of medical genetics
  • 2000
Fetomaternal cell trafficking provides a potential explanation for the increased prevalence of autoimmune disorders in adult women following their childbearing years, and the realization that following pregnancy, a woman becomes a chimera.

Are Fetal Cells in Maternal Blood Mainly B Lymphocytes?

Most fetal cells in maternal blood adhere to nylon wool, as do B lymphocytes, but this adherence is to some extent affected by pronase incubation.

Transplacental passage of foetal blood cells.

The findings suggest that foetal lymphocytes pass actively into the mother's blood relatively early during pregnancy, and may remain in the maternal blood for long periods.

Significant fetal-maternal hemorrhage after termination of pregnancy: implications for development of fetal cell microchimerism.

Analysis by quantitative polymerase chain reaction amplification demonstrated a large fetal-maternal transfusion after elective abortion, indicating the potential for future development of fetal cell microchimerism must now extend to a larger population of women.