FETAL LEUKOCYTES IN THE MATERNAL CIRCULATION AFTER DELIVERY: Cytological Aspects

@article{Schrder1974FETALLI,
  title={FETAL LEUKOCYTES IN THE MATERNAL CIRCULATION AFTER DELIVERY: Cytological Aspects},
  author={Jim Schr{\"o}der and Anja Thlikainen and Albert de la Chapelle},
  journal={Transplantation},
  year={1974},
  volume={17},
  pages={346-354}
}
The presence of fetal cells in the maternal circulation after delivery was investigated by examining interphase cells for fluorescent Y-bodies after staining with quinacrine mustard. Mothers were excluded if their own autosomos had regions of brilliant fluorescence that simulated Y-bodies. In a study of 24 primiparas, the sex of whose children was unknown to the observer, the method was found to be reliable: 34 of the 240,000 cells examined showed a presumptive Y-body, and only one of these… 
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Background Citations
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130 Citations

Fetal cells in the maternal blood

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Fetal cells in the blood of pregnant mothers.

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Fetal nucleated cells in maternal peripheral blood after delivery.

Fetal nucleated cells in maternal peripheral blood: frequency and relationship to gestational age

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Isolating fetal cells in maternal circulation for prenatal diagnosis

Polymerase chain reaction (PCR) technology is considered appropriate to offer this technology as an alternative to conventional invasive and non‐invasive methods of prenatal cytogenetic diagnosis only upon completion of clinical evaluations.

Fetomaternal cell trafficking: a new cause of disease?

  • D. Bianchi
  • Medicine, Biology
    American journal of medical genetics
  • 2000
Fetomaternal cell trafficking provides a potential explanation for the increased prevalence of autoimmune disorders in adult women following their childbearing years, and the realization that following pregnancy, a woman becomes a chimera.

Are Fetal Cells in Maternal Blood Mainly B Lymphocytes?

Most fetal cells in maternal blood adhere to nylon wool, as do B lymphocytes, but this adherence is to some extent affected by pronase incubation.

Transplacental passage of foetal blood cells.

The findings suggest that foetal lymphocytes pass actively into the mother's blood relatively early during pregnancy, and may remain in the maternal blood for long periods.

Significant fetal-maternal hemorrhage after termination of pregnancy: implications for development of fetal cell microchimerism.

Analysis by quantitative polymerase chain reaction amplification demonstrated a large fetal-maternal transfusion after elective abortion, indicating the potential for future development of fetal cell microchimerism must now extend to a larger population of women.
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