FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading

@article{Poepperl2007FETPF,
  title={FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading},
  author={Gabriele Poepperl and Friedrich Wilhelm Kreth and Jan Hendrik Mehrkens and Jochen Herms and Klaus Christian Seelos and Walter A. Koch and Franz Josef Gildehaus and Hans A. Kretzschmar and Joerg Christian Tonn and Klaus Tatsch},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2007},
  volume={34},
  pages={1933-1942}
}
Treatment and prognosis of gliomas depend on their histological tumour grade. The aim of the study was to evaluate the potential of [18F]fluoroethyltyrosine (FET) PET for non-invasive tumour grading in untreated patients. Dynamic FET PET studies were performed in 54 patients who, based on MRI, were estimated to have low grade (LG; n = 20), intermediate (WHO II–III; n = 4) or high grade (HG; n = 30) tumours. For standard evaluation, tumour SUVmax and the ratio to background (SUVmax/BG) were… CONTINUE READING

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