FEEDBACK INHIBITION OF SPECIFICALLY SENSITIZED LYMPHOCYTES

@article{Mackaness1974FEEDBACKIO,
  title={FEEDBACK INHIBITION OF SPECIFICALLY SENSITIZED LYMPHOCYTES},
  author={G. Mackaness and P. Lagrange and T. Miller and T. Ishibashi},
  journal={The Journal of Experimental Medicine},
  year={1974},
  volume={139},
  pages={543 - 559}
}
An explanation was sought for the fact that delayed-type hypersensitivity (DTH) does not normally occur in response to T-cell-dependent antigens unless an adjuvant is used. But when sheep red blood cells (SRBC) were administered intravenously DTH did appear, provided that the dose of antigen was less than that required to give a maximum antibody response. Animals in which T-cell activity had been blocked by a large dose of antigen could not be sensitized adoptively, and their spleen cells… Expand
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References

SHOWING 1-10 OF 32 REFERENCES
INFLUENCE OF DOSE AND ROUTE OF ANTIGEN INJECTION ON THE IMMUNOLOGICAL INDUCTION OF T CELLS
  • 314
  • PDF
THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO
  • G. Mackaness
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1969
  • 781
  • PDF
CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO
  • M. Feldmann
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1972
  • 246
  • PDF
Regulation of the immune response with antigen specific IgM antibody: a dual role.
  • 37
Suggestive evidence that the "blocking antibodies" of tumor-bearing individuals may be antigen--antibody complexes.
  • 659
  • PDF
The mechanism of antibody-induced stimulation and inhibition of the immune response.
  • G. Dennert
  • Biology, Medicine
  • Journal of immunology
  • 1971
  • 74
CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO
  • M. Feldmann
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1972
  • 173
  • PDF
THE COMPARTMENTALIZATION OF ANTIGEN-REACTIVE LYMPHOCYTES IN DESENSITIZED GUINEA PIGS
  • 60
  • PDF
THE IMMUNE RESPONSE IN THE PRESENCE OF DELAYED HYPERSENSITIVITY OF CIRCULATING ANTIBODY.
  • 32
...
1
2
3
4
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