FDG-PET reveals improved cardiac regeneration and attenuated adverse remodelling following Sitagliptin + G-CSF therapy after acute myocardial infarction.

@article{Gross2016FDGPETRI,
  title={FDG-PET reveals improved cardiac regeneration and attenuated adverse remodelling following Sitagliptin + G-CSF therapy after acute myocardial infarction.},
  author={Lisa M. Gross and Lisa Paintmayer and Sebastian Lehner and Lydia Brandl and Christoph Brenner and Ulrich Grabmaier and Bruno C. Huber and Peter Bartenstein and H Theiss and Wolfgang Michael Franz and Steffen Massberg and Andrei Todica and Stefan Brunner},
  journal={European heart journal cardiovascular Imaging},
  year={2016},
  volume={17 2},
  pages={136-45}
}
AIMS Dual therapy comprising G-CSF for mobilization of bone marrow-derived progenitor cells (BMPCs), with simultaneous pharmacological inhibition of dipeptidylpeptidase-IV for enhanced myocardial recruitment of circulating BMPC via the SDF-1α/CXCR4-axis, has been shown to improve survival after acute myocardial infarction (AMI). Using an innovative method to provide non-invasive serial in vivo measurements and information on metabolic processes, we aimed to substantiate the possible effects of… CONTINUE READING
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