FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma

@inproceedings{Wang2013FBX8AA,
  title={FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma},
  author={Feifei Wang and Yudan Qiao and Jiang Yu and Xiaoli Ren and Jianmei Wang and Yi Ding and Xiaojing Zhang and Wenhui Ma and Yanqing Ding and Li Liang},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND F-box only protein 8 (FBX8), a novel component of F-box proteins, is lost in several cancers and has been associated with invasiveness of cancer cells. However, its expression pattern and role in the progression of hepatocellular carcinoma remain unclear. This study investigated the prognostic significance of FBX8 in hepatocellular carcinoma samples and analyzed FBX8 function in hepatocellular carcinoma cells by gene manipulation. METHODOLOGY The expression of FBX8 was detected in… CONTINUE READING

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