FBPs are calibrated molecular tools to adjust gene expression.

  title={FBPs are calibrated molecular tools to adjust gene expression.},
  author={H Chung and Juhong Liu and Miroslav Dundr and Zuqin Nie and Suzanne Sanford and David Levens},
  journal={Molecular and cellular biology},
  volume={26 17},
The three far-upstream element (FUSE) binding protein (FBP) family members have been ascribed different functions in gene regulation. They were therefore examined with various biochemical, molecular biological, and cell biological tests to evaluate whether their sequence differences reflect functional customization or neutral changes at unselected residues. Each FBP displayed a characteristic profile of intrinsic transcription activation and repression, binding with protein partners, and… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 37 extracted citations

Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…