FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial.

@article{Mortensen2012FAZAPH,
  title={FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial.},
  author={L. S. Mortensen and J. Johansen and J. Kallehauge and H. Primdahl and M. Busk and P. Lassen and J. Alsner and B. S. S{\o}rensen and K. Toustrup and S. Jakobsen and J. Petersen and H. Petersen and J. Theil and M. Nordsmark and J. Overgaard},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2012},
  volume={105 1},
  pages={
          14-20
        }
}
PURPOSE Hypoxia is a cause of resistance to radiotherapy, especially in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to evaluate (18)F-fluoroazomycin arabinoside (FAZA) positron emission tomography (PET)/computed tomography (CT) hypoxia imaging as a prognostic factor in HNSCC patients receiving radiotherapy. MATERIAL AND METHODS Forty patients with HNSCC treated with radiotherapy (66-76 Gy) were included. Static FAZA PET/CT imaging 2h post… Expand
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