FAT is a component of glomerular slit diaphragms.

  title={FAT is a component of glomerular slit diaphragms.},
  author={Tomohiro Inoue and Eishin Yaoita and Hidetake Kurihara and Fujio Shimizu and Tatsuo Sakai and Tsutomu Kobayashi and Kenji Ohshiro and Hiroshi Kawachi and Hidechika Okada and Hiromichi Suzuki and Itaru Kihara and Tadashi Yamamoto},
  journal={Kidney international},
  volume={59 3},
BACKGROUND Slit diaphragms are intercellular junctions of podocytes of the renal glomerulus. The molecular composition of slit diaphragms is still elusive. Slit diaphragms are characterized by the presence of a wide intercellular space. The morphological feature is shared by desmosomes and adherens junctions, which contain members of the cadherin superfamily. Thus, we have hypothesized that some components of slit diaphragms belong to the cadherin superfamily. Consequently, we have isolated… CONTINUE READING


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