FAF-Drugs: free ADME/tox filtering of compound collections

@article{Miteva2006FAFDrugsFA,
  title={FAF-Drugs: free ADME/tox filtering of compound collections},
  author={Maria A. Miteva and Stephanie Violas and Matthieu Montes and David Gomez and Pierre Tuff{\'e}ry and Bruno O. Villoutreix},
  journal={Nucleic Acids Research},
  year={2006},
  volume={34},
  pages={W738 - W744}
}
In silico screening based on the structures of the ligands or of the receptors has become an essential tool to facilitate the drug discovery process but compound collections are needed to carry out such in silico experiments. It has been recognized that absorption, distribution, metabolism, excretion and toxicity (ADME/tox) are key properties that need to be considered early on, even during the database preparation stage. FAF-Drugs is an online service based on Frowns (a chemoinformatics… CONTINUE READING

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