FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases

@article{Lattka2009FADSGC,
  title={FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases},
  author={E. Lattka and T. Illig and J. Heinrich and B. Koletzko},
  journal={Lifestyle Genomics},
  year={2009},
  volume={2},
  pages={119 - 128}
}
  • E. Lattka, T. Illig, +1 author B. Koletzko
  • Published 2009
  • Biology, Medicine
  • Lifestyle Genomics
  • Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease. The level and composition of LC-PUFAs in the human body is highly dependent on their intake in the diet or on the intake of fatty acid precursors, which are endogenously elongated and desaturated to physiologically active LC-PUFAs. The most important enzymes in this reaction… CONTINUE READING
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