F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis

Abstract

During the release of sperm at spermiation, a biologically active F5-peptide, which can disrupt the Sertoli cell tight junction (TJ) permeability barrier, is produced at the site of the degenerating apical ES (ectoplasmic specialization). This peptide coordinates the events of spermiation and blood-testis barrier (BTB) remodeling at stage VIII of the… (More)
DOI: 10.18632/oncotarget.11887

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Cite this paper

@inproceedings{Gao2016F5peptideIA, title={F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis}, author={Ying Gao and Dolores D. Mruk and Wing-yee Lui and Will W M Lee and C Yan Cheng}, booktitle={Oncotarget}, year={2016} }