F-actin network formation in tethers and in pseudopods stimulated by chemoattractant.

@article{Zhelev1996FactinNF,
  title={F-actin network formation in tethers and in pseudopods stimulated by chemoattractant.},
  author={Doncho V. Zhelev and Abdullatif M Alteraifi and Robert M. Hochmuth},
  journal={Cell motility and the cytoskeleton},
  year={1996},
  volume={35 4},
  pages={331-44}
}
Micropipets are used either to deliver a given concentration of the chemoattractant N-formyl-methionyl-leucyl-phenylalanine (fMLP) to a local region of a human neutrophil or to create a membrane tether. Pseudopods, which have a cylindrical shape and grow at a constant rate, are formed in either case. After reaching a maximum extension, they retract, even in the presence of chemoattractant. As a pseudopod grows, cell granules begin to penetrate the pseudopod region to a "boundary" that defines a… CONTINUE READING
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