Ezrin expression predicts local recurrence and development of metastases in soft tissue sarcomas.

@article{Carneiro2011EzrinEP,
  title={Ezrin expression predicts local recurrence and development of metastases in soft tissue sarcomas.},
  author={Ana Suellen B Carneiro and P{\"a}r-Ola Bendahl and M{\aa}ns {\AA}kerman and Henryk A. Domanski and Anders Rydholm and Jacob Engellau and Mef Nilbert},
  journal={Journal of clinical pathology},
  year={2011},
  volume={64 8},
  pages={
          689-94
        }
}
BACKGROUND Ezrin is a cytoskeletal protein involved in tumour growth and invasion. Ezrin expression has been suggested to play a role in metastasis in paediatric osteosarcoma and rhabdomyosarcoma. AIM To evaluate the prognostic role of ezrin in a large series of soft tissue sarcoma of the extremities and trunk wall. METHODS Ezrin expression was evaluated by immunohistochemistry on tissue microarrays from a mixed series of 256 soft tissue sarcomas. The expression patterns were correlated to… CONTINUE READING
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