Ezrin, a key component in tumor metastasis.

  title={Ezrin, a key component in tumor metastasis.},
  author={Kent W Hunter},
  journal={Trends in molecular medicine},
  volume={10 5},
Identification of the key regulatory molecules in metastasis is crucial for understanding tumor dissemination and for the development of novel interventions. The recent identification of ezrin as a necessary component in the metastasis of osteosarcoma and rhabdomyosarcoma is, therefore, an important advance. Ezrin has been implicated in many roles, for example, as a conduit for signals between metastasis-associated cell-surface molecules and signal transduction components. This suggests that… CONTINUE READING