Eye development and photoreceptor differentiation in the cephalopod Doryteuthis pealeii

  title={Eye development and photoreceptor differentiation in the cephalopod Doryteuthis pealeii},
  author={Kristen M. Koenig and Peter Sun and Eli Meyer and Jeffrey M. Gross},
  pages={3168 - 3181}
Photoreception is a ubiquitous sensory ability found across the Metazoa, and photoreceptive organs are intricate and diverse in their structure. Although the morphology of the compound eye in Drosophila and the single-chambered eye in vertebrates have elaborated independently, the amount of conservation within the ‘eye’ gene regulatory network remains controversial, with few taxa studied. To better understand the evolution of photoreceptive organs, we established the cephalopod Doryteuthis… 
Eye Development in Sepia officinalis Embryo: What the Uncommon Gene Expression Profiles Tell Us about Eye Evolution
For the first time, Sof-rhodopsin expression is shown in the embryonic retina of cuttlefish suggesting the evolutionary conservation of the role of r Rhodopsin in visual phototransduction within metazoans.
Co-option of the limb patterning program in cephalopod eye development
This study suggests that this canonical bilaterian limb patterning program could perform a more universal developmental function in radial patterning and highlights how canonical genetic programs are repurposed in novel structures.
A single-cell atlas of bobtail squid visual and nervous system highlights molecular principles of convergent evolution
Genomics and single cell transcriptomics are used to study mechanisms in the visual system of the bobtail squid Euprymna berryi, an emerging cephalopod model to observe changes in cell populations and neurotransmitter usage during maturation and growth of the visual systems from hatchling to adult.
Co-option of the Limb Patterning Program in Cephalopod Lens Development
The co-option of the canonical bilaterian limb pattering program redeployed during cephalopod lens development is identified and radial expression of transcription factors SP6-9/sp1, Dlx/dll, Pbx/exd, Meis/hth, and a Prdl homolog in the squid Doryteuthis pealeii is shown, similar to expression required in Drosophila limb development.
Cephalopod Brains: An Overview of Current Knowledge to Facilitate Comparison With Vertebrates
A critical analysis of cephalopod neural systems showing similarities to the cerebral cortex, thalamus, basal ganglia, midbrain, cerebellum, hypothalamus, brain stem, and spinal cord of vertebrates is described.
Embryonic development of the camouflaging dwarf cuttlefish, Sepia bandensis
The dwarf cuttlefish Sepia bandensis, a camouflaging cephalopod from the Indo‐Pacific, is a promising new model organism for neuroscience, developmental biology, and evolutionary studies and has a striking ability to regenerate their limbs.
Krüppel-like factor/specificity protein evolution in the Spiralia and the implications for cephalopod visual system novelties
The hypothesis that gene duplication and neofunctionalization contribute to novel traits like the cephalopod image-forming eye and to the diversity found within Spiralia is supported.
Octopus insularis as a new marine model for evolutionary developmental biology
It is proposed that O. insularis embryos could be used as a model for evolutionary developmental biology (or EvoDevo) research, where comparisons of the morphogenetic steps in the building of equivalent organs between cephalopods and known vertebrate model systems could shed light on evolutionary convergences and deep homologies.
Cephalopod Biology: At the Intersection Between Genomic and Organismal Novelties.
This review addresses the recent progress and impact of genomic and other molecular resources on research in cephalopods and outlines several key directions in which significant progress is expected and its impact on the understanding of the genetic background behind cEPhalopod biology and beyond.


Genetic mechanisms involved in the evolution of the cephalopod camera eye revealed by transcriptomic and developmental studies
The results of this study suggest that changes in gene expression and in the primary structure of proteins from those in the common molluscan ancestor could have contributed, at least in part, to cephalopod camera eye acquisition.
Engrailed in cephalopods: a key gene related to the emergence of morphological novelties
An engrailed cognate is identified in the squid Loligo, which provides new evidence that engrailing in molluscs is not restricted to a ‘shell function’ and has been recruited in the mollusc lineage for the emergence of morphological novelties in cephalopods.
The octopus genome and the evolution of cephalopod neural and morphological novelties
Coleoid cephalopods (octopus, squid and cuttlefish) are active, resourceful predators with a rich behavioural repertoire. They have the largest nervous systems among the invertebrates and present
New perspectives on eye development and the evolution of eyes and photoreceptors.
The demonstration that targeted expression of one and the same master control gene, that is, Pax6 can induce the formation of ectopic eyes in both insects and vertebrates necessitates a reconsideration of the dogma of a polyphyletic origin of the various eye types in all the animal phyla.
Evolution of eyes and photoreceptor cell types.
  • D. Arendt
  • Biology
    The International journal of developmental biology
  • 2003
It is proposed that the retinal ganglion, amacrine and horizontal cells are evolutionary sister cell types that evolved from a common rhabdomeric photoreceptor cell precursor, the proto-eye.
Cephalopod Hox genes and the origin of morphological novelties
Developmental expression patterns for eight out of nine Hox genes in the Hawaiian bobtail squid Euprymna scolopes are examined by whole-mount in situ hybridization, showing that Hox orthologues have been recruited multiple times and in many ways in the origin of new cephalopod structures.