Eye‐sparing multidisciplinary approach for the management of lacrimal gland carcinoma

@article{Esmaeli2016EyesparingMA,
  title={Eye‐sparing multidisciplinary approach for the management of lacrimal gland carcinoma},
  author={Bita Esmaeli and Vivian T. Yin and Ehab Y. Hanna and Merrill S. Kies and William N. William and Diana Bell and Steven J. Frank},
  journal={Head \& Neck},
  year={2016},
  volume={38}
}
We analyzed local control and early ocular toxicity after eye‐sparing management of lacrimal gland carcinoma. 
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Outcomes after eye‐sparing surgery vs orbital exenteration in patients with lacrimal gland carcinoma
This study examined whether eye‐sparing surgery is associated with better or worse outcomes than exenteration for the treatment of lacrimal gland carcinomas.
Intraorbital Pathology (Tumors) and Management Strategies
Case of Adenoid Cystic Carcinoma of Lacrimal Gland Treated by Eye Sparing Radiation Therapy using 3DCRT Technique
TLDR
The following case illustrates the interdisciplinary approach to a rare tumor entity and the considerations made for preserving the orbital structures functionally.
Lacrimal gland adenoid cystic carcinoma: report of an unusual case with literature review
TLDR
A case of lacrimal gland adenoid cystic carcinoma treated with orbital exenteration and adjuvant volumetric modulated arc therapy is introduced, and the related literature is discussed.
Overview of benign and malignant lacrimal gland tumors
TLDR
Intra-arterial chemotherapy has been found to decrease recurrence and improve survival in ACC and can be used as part of an eye-sparing treatment strategy and the development of targeted drugs may offer palliation for patients with unresectable or metastatic disease in lacrimal gland carcinoma.
Current treatment of lacrimal gland carcinoma
TLDR
In selected patients with lacrimal gland carcinoma, eye- Sparing surgery with eye-sparing radiation therapy offers preservation of visual function with good local control and minimal radiation-induced ocular toxic effects, and a search for actionable cancer-associated mutations may be prudent.
Survival outcomes of eye-sparing surgery for adenoid cystic carcinoma of lacrimal gland
TLDR
This study highlighted the aggressive nature of adenoid cystic carcinoma of lacrimal glands and found that eye-sparing surgery with adjunctive radiotherapy may achieve relatively optimal disease control in diseases staged T1 or T2, but in advanced disease metastasis and mortality are usually inevitable.
Multimodal therapy in the management of lacrimal gland adenoid cystic carcinoma
TLDR
Eye-sparing tumor resection protocol followed by adjuvant therapy seems to be associated with high rates of local recurrence, metastases and death in Chinese patients with lacrimal gland adenoid cystic carcinoma with ≥ T3a tumors.
Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old male
TLDR
A case of lacrimal gland ACC is reported in a 14-year-old male treated with neoadjuvant intra-arterial chemotherapy followed by globe-sparing tumor resection and chemoradiation and he remains disease free without evidence of tumor recurrence.
An Update on Tumors of the Lacrimal Gland.
TLDR
An update on the clinical, radiological, histological, and molecular features, along with treatment strategies for tumors of the lacrimal gland are presented.
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