Extrusions are phagocytosed and promote Chlamydia survival within macrophages.

  title={Extrusions are phagocytosed and promote Chlamydia survival within macrophages.},
  author={Meghan E Zuck and Tisha Ellis and Anthony Venida and Kevin Hybiske},
  journal={Cellular microbiology},
  volume={19 4}
The precise strategies that intracellular pathogens use to exit host cells have a direct impact on their ability to disseminate within a host, transmit to new hosts, and engage or avoid immune responses. The obligate intracellular bacterium Chlamydia trachomatis exits the host cell by two distinct exit strategies, lysis and extrusion. The defining characteristics of extrusions, and advantages gained by Chlamydia within this unique double-membrane structure, are not well understood. Here, we… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 6 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…