Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy.

@article{Unuma2015ExtrusionOM,
  title={Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy.},
  author={Kana Unuma and Toshihiko Aki and Takeshi Funakoshi and Kyoko Hashimoto and Koichi Uemura},
  journal={Autophagy},
  year={2015},
  volume={11 9},
  pages={1520-36}
}
Sepsis/endotoxemia is elicited by the circulatory distribution of pathogens/endotoxins into whole bodies, and causes profound effects on human health by causing inflammation in multiple organs. Mitochondrial damage is one of the characteristics of the cellular degeneration observed during sepsis/endotoxemia. Elimination of damaged mitochondria through the autophagy-lysosome system has been reported in the liver, indicating that autophagy should play an important role in liver homeostasis during… CONTINUE READING
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