Extrinsic allergic alveolitis

  title={Extrinsic allergic alveolitis},
  author={Tengku Ismail and Charles McSharry and Gavin Boyd},
Abstract:  Extrinsic allergic alveolitis (also known as hypersensitivity pneumonitis) is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response in the distal bronchioles and alveoli and subjects may present clinically with a variety of symptoms. The aims of this review are to describe the current concepts of the immunological response, the diverse clinical presentation of this disease, the relevant investigations and management… 

Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) Caused by Sphingobacterium spiritivorum from the Water Reservoir of a Steam Iron

A case of extrinsic allergic alveolitis (EAA) caused by Sphingobacterium spiritivorum is described, the first report of S.spiritivorum as a causative agent of EAA.

Hypersensitivity pneumonitis

Hypersensitivity pneumonitis is a pulmonary disease with symptoms of cough and dyspnea resulting from the inhalation of an antigen to which the subject has been previously sensitized,such as

Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma.

It is proposed that asthma allergens cause severe noneosinophilic asthma because of sensitization in the presence of hypersensitivity pneumonitis-promoting danger signaling.

Extrinsic allergic alveolitis as an uncommon diagnostic pitfall in lung cytology

A biopsy‐proven case of extrinsic allergic alveolitis (EAA) who presented with nonspecific respiratory symptoms 1 month after having her whole house interior painted who received short‐term steroid treatment and has been doing well for the last 7 months after her operation.

Allergic Asthma and Rhinitis: Toxicological Considerations

The complexity of the allergic response in terms of humoral and cell-mediated immunity, as well as potential differences in mechanisms depending on the allergen, present a very challenging scenario for the toxicologist to predict the exposures that will result in allergic rhinitis or asthma.

Working with argan cake: a new etiology for hypersensitivity pneumonitis

The first evidence of hypersensitivity pneumonitis related to argan powder in two patients is reported, implying preventive measures to reduce their exposure and clinical survey to diagnose early symptoms.

Hypersensitivity pneumonitis caused by occupational exposure to phytase

The patient worked in a cattle feed factory and noticed that he had more complaints after his working hours, and his symptoms could be ascribed to hypersensitivity pneumonitis due to contact with phytase, an enzyme added to cattle feed to strengthen bone and diminish phosphorus excretion.



Takes your breath away – the immunology of allergic alveolitis

The aims of this review are to describe current concepts of the immunology of this model of lung inflammation, to describe some of the constitutional and environmental characteristics which affect disease susceptibility and development, and to describe topics for prospective study.

Extrinsic allergic alveolitis (hypersensitivity pneumonitis): past, present and future

  • J. Salvaggio
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1997
The history of occupational and environmental pulmonary diseases associated with exposure to organic dusts and what I believe to be the present state-of-the-art related to this subject are discussed.

Hypersensitivity pneumonitis: patterns on high-resolution CT.

In this pictorial essay, the high-resolution CT patterns of hypersensitivity pneumonitis are illustrated and the authors emphasize the correlation among the radiologic presentation, functional abnormalities, and pathologic findings.

Hypersensitivity pneumonitis: current concepts.

Hypersensitivity pneumonitis (HP), or extrinsic allergic alveolitis, is due to a hypersensitivity reaction after repeated inhalation of finely dispersed antigens, mainly organic particles or low

Needs and opportunities for research in hypersensitivity pneumonitis.

A workshop recommended a population-based study to more accurately document the incidence and prevalence of HP, and better classification of disease stages, including natural history and evaluation of diagnostic tests and biomarkers used to detect disease.

Bronchoalveolar lavage in extrinsic allergic alveolitis: effect of time elapsed since antigen exposure.

It is demonstrated that bronchoalveolar lavage cell profile and immunoglobulin levels in EAA are highly dependent on the time-point at which the material is obtained in relation to the last exposure to the causative antigen.

Clinical and radiologic manifestations of hypersensitivity pneumonitis.

The combination of a mosaic pattern with ground-glass opacification and centrilobular nodules is particularly suggestive of the diagnosis and the best long-term prognosis is achieved with early diagnosis and removal from exposure.

Longitudinal study of alveolitis in hypersensitivity pneumonitis patients: an immunologic evaluation.

Development of bronchus-associated lymphoid tissue in chronic hypersensitivity pneumonitis.

Observations suggest that chronic antigenic stimulation and/or inflammation in CHP may cause BALT development, which, in turn, is likely to play an important role in the mucosal immune response of this disease.

Protective value of dust respirators in extrinsic allergic alveolitis: clinical assessment using inhalation provocation tests.

It is concluded that respirators of this type can offer substantial, and in most cases complete, protection against single exposures to environmental dusts that may provoke extrinsic allergic alveolitis.