Extremely reduced levels of heterozygosity in the vertebrate pathogen Encephalitozoon cuniculi.

@article{Selman2013ExtremelyRL,
  title={Extremely reduced levels of heterozygosity in the vertebrate pathogen Encephalitozoon cuniculi.},
  author={Mohammed Selman and B Sak and Martin Kv{\'a}{\vc} and Laurent Farinelli and Louis M Weiss and Nicolas Corradi},
  journal={Eukaryotic cell},
  year={2013},
  volume={12 4},
  pages={496-502}
}
The genomes of microsporidia in the genus Encephalitozoon have been extensively studied for their minimalistic features, but they have seldom been used to investigate basic characteristics of the biology of these organisms, such as their ploidy or their mode of reproduction. In the present study, we aimed to tackle this issue by mapping Illumina sequence reads against the genomes of four strains of E. cuniculi. This approach, combined with more conventional molecular biology techniques… CONTINUE READING

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