Extremely high major histocompatibility complex class IIb gene intron 2 variation and population structure in Chinese alligator

@article{Nie2012ExtremelyHM,
  title={Extremely high major histocompatibility complex class IIb gene intron 2 variation and population structure in Chinese alligator},
  author={Chuanpeng Nie and Yanyan Li and Juan Zhao and Xiaobing Wu},
  journal={Journal of Genetics},
  year={2012},
  volume={93},
  pages={86-91}
}
Identifying the processes that maintain genetic diversity within and among populations is a central goal of modern evolutionary genetics. So far, the studies on genetic diversity have mainly focussed on neutral DNA markers, such as mtDNA and microsatellites (Xu et al. 2010). While these markers are very informative in molecular clocks, to examine dispersal patterns of individuals (gene flow) and to classify them by relatedness and paternity analyses. The variation at neutral loci cannot provide… 
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References

SHOWING 1-10 OF 25 REFERENCES
The importance of immune gene variability (MHC) in evolutionary ecology and conservation
  • S. Sommer
  • Biology, Medicine
    Frontiers in Zoology
  • 2005
TLDR
Empirical support for the functional importance of MHC variability in parasite resistance is summarised with emphasis on the evidence derived from free-ranging animal populations investigated in their natural habitat.
High allelic variation of MHC class II alpha antigen and the role of selection in wild and cultured Sparus aurata populations
TLDR
Comparison with previously published results on microsatellite markers suggests that balancing selection in MHC genes reduces the genetic drift and bottleneck effects that are common in aquaculture and which are known to reduce genetic variation at neutral markers.
Selection, trans-species polymorphism, and locus identification of major histocompatibility complex class IIβ alleles of New World ranid frogs
TLDR
The results indicated that primer mismatch can result in polymerase chain reaction (PCR) bias, which influences the number of alleles that are recovered, and the gene walking technique was an effective approach for generating single-copy orthologous markers necessary for future studies of MHC allelic variation in natural amphibian populations.
Genetic drift outweighs balancing selection in shaping post‐bottleneck major histocompatibility complex variation in New Zealand robins (Petroicidae)
TLDR
Comparison of MHC variation with minisatellite DNA variation indicates that genetic drift outweighs balancing selection in determining MHC diversity in the bottlenecked populations, however, balancing selection appears to influence MHC Diversity over evolutionary timescales, and the effects of gene conversion are evident.
Sequence Polymorphism and Geographical Variation at a Positively Selected MHC-DRB Gene in the Finless Porpoise (Neophocaena phocaenoides): Implication for Recent Differentiation of the Yangtze Finless Porpoise?
TLDR
Porpoises from the Yangtze River displayed divergent frequencies of shared and private alleles from those displayed by two marine populations, which suggest that the former riverine population has been under a different selection regime (characteristic of a fresh water environment) than that of its marine counterparts.
Polymorphism of exon 3 of MHC class II B gene in Chinese alligator (Alligator sinensis).
TLDR
The nucleotide diversity of the sequences and the phylogenetic relations were analyzed, and the results suggested that there was no significant difference in genetic diversity among the 3 populations of Chinese alligator.
Contemporary fisherian life-history evolution in small salmonid populations
TLDR
It is shown that natural selection was the dominant diversifying agent in the evolution of the quantitative traits in isolated populations of grayling that originated from a common source 80–120 years ago.
[D-loop sequence variation of mitochondrial DNA in captive Chinese alligator].
Chinese alligator, Alligator sinensis, is a critically endangered endemic species under legislative protection in China. Result of recent investigations revealed that number of the alligators was
Genetic diversity of Chinese alligator (Alligator sinensis) revealed by AFLP analysis: an implication on the management of captive conservation
TLDR
Electrophoresis profile displayed 3 individuals possessing very highly polymorphic AFLP phenotypes that were never been found by RAPD and mtDNA D-loop sequencing, implicating that these individuals should offer these individuals more breeding opportunities to maintain the genetic diversity in the population and restrict those carrying few polymorphic loci from reproduction.
Genetic variation in captive population of chinese alligator, Alligator sinensis, revealed by random amplified polymorphic DNA (RAPD)
TLDR
A preliminary research on genetic structure in populations of Chinese alligator concludes that according to the dendrogram and the distribution of polymorphic fragments in two subpopulations, CXSP originated genetically from XZSP, and the founder effect is a possible explanation for very low genetic variation in CX SP.
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