Extreme stretch growth of integrated axons.

  title={Extreme stretch growth of integrated axons.},
  author={Bryan J. Pfister and Akira Iwata and David F. Meaney and Douglas H. Smith},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={24 36},
Large animals can undergo enormous growth during development, suggesting that axons in nerves and white matter tracts rapidly expand as well. Because integrated axons have no growth cones to extend from, it has been postulated that mechanical forces may stimulate axon elongation matching the growth of the animal. However, this distinct form of rapid and sustained growth of integrated axons has never been demonstrated. Here, we used a microstepper motor system to evaluate the effects of… CONTINUE READING

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