Extreme sequence heteroplasmy in bat mitochondrial DNA.

  title={Extreme sequence heteroplasmy in bat mitochondrial DNA.},
  author={Barbara Petri and Arndt von Haeseler and Svante P{\"a}{\"a}bo},
  journal={Biological chemistry},
  volume={377 10},
Mitochondrial heteroplasmy is shown to be extensive when amplification products from the mitochondrial control region are cloned and sequenced from a European bat species. In contrast, a mitochondrial ribosomal RNA gene does not exhibit substantial levels of heteroplasmy when analyzed in an identical way. In the bat, heteroplasmy with respect to length as well as sequence seems to be transmitted from mother to offspring. Thus, the intra-individual sequence diversity seems to accumulate within… CONTINUE READING


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Identification of the remains of the Romanov family by DNA analysis

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