Extreme inbreeding in Leishmania braziliensis.

  title={Extreme inbreeding in Leishmania braziliensis.},
  author={Virginie Rougeron and Thierry De Mee{\^u}s and Mallorie Hide and Etienne Waleckx and Herman Bermudez and Jorge Ar{\'e}valo and Alejandro Llanos-Cuentas and J M Dujardin and Simone De Doncker and Dominique Le Ray and Francisco J. Ayala and Anne-Laure Ba{\~n}uls},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 25},
Leishmania species of the subgenus Viannia and especially Leishmania braziliensis are responsible for a large proportion of New World leishmaniasis cases. The reproductive mode of Leishmania species has often been assumed to be predominantly clonal, but remains unsettled. We have investigated the genetic polymorphism at 12 microsatellite loci on 124 human strains of Leishmania braziliensis from 2 countries, Peru and Bolivia. There is substantial genetic diversity, with an average of 12.4 +/- 4… CONTINUE READING

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