Extreme MHC class I diversity in the sedge warbler (Acrocephalus schoenobaenus); selection patterns and allelic divergence suggest that different genes have different functions

@inproceedings{Biedrzycka2017ExtremeMC,
  title={Extreme MHC class I diversity in the sedge warbler (Acrocephalus schoenobaenus); selection patterns and allelic divergence suggest that different genes have different functions},
  author={Aleksandra Biedrzycka and Emily A O'Connor and Alvaro San Sebasti{\'a}n and Magdalena Migalska and Jacek Radwan and Tadeusz Zając and Wojciech Bielański and Wojciech Solarz and Adam M {\'C}miel and Helena Westerdahl},
  booktitle={BMC Evolutionary Biology},
  year={2017}
}
BackgroundRecent work suggests that gene duplications may play an important role in the evolution of immunity genes. Passerine birds, and in particular Sylvioidea warblers, have highly duplicated major histocompatibility complex (MHC) genes, which are key in immunity, compared to other vertebrates. However, reasons for this high MHC gene copy number are yet unclear. High-throughput sequencing (HTS) allows MHC genotyping even in individuals with extremely duplicated genes. This HTS data can… CONTINUE READING
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M Kearse, R Moir, +4 authors basic et al. Geneious
  • BMC Evolutionary Biology
  • 2017