Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis.

@article{Marrazzo2012ExtravaginalRO,
  title={Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis.},
  author={Jeanne M Marrazzo and Tina L. Fiedler and Sujatha Srinivasan and Katherine Thomas and Congzhou Liu and Daisy L. Ko and Hu Xie and Misty Saracino and David N. Fredricks},
  journal={The Journal of infectious diseases},
  year={2012},
  volume={205 10},
  pages={1580-8}
}
BACKGROUND Bacterial vaginosis (BV) represents shifts in microbiota from Lactobacillus spp. to diverse anaerobes. Although antibiotics relieve symptoms and temporarily eradicate BV-associated bacteria (BVAB), BV usually recurs. We investigated the role of extravaginal BVAB reservoirs in recurrence. METHODS Risks for BV acquisition over the course of 1 year were defined. DNA in vaginal, anal, and oral swab samples from enrollment was subjected to quantitative polymerase chain reaction assays… CONTINUE READING