Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

@inproceedings{Trueta2012ExtrasynapticEA,
  title={Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system},
  author={Citlali Trueta and Francisco F. De-Miguel},
  booktitle={Front. Physio.},
  year={2012}
}
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites, and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, with emphasis on somatic exocytosis, and how it contributes to signaling in the nervous system. The finding of secretory vesicles in extrasynaptic sites of neurons, the presence of signaling molecules (namely transmitters or peptides) in the extracellular space outside synaptic clefts, and the mismatch between… CONTINUE READING

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Volume transmission in the brain: beyond the synapse.

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CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 245 REFERENCES

Activity-dependent vesicular monoamine transporter-mediated depletion of the nucleus supports somatic release by serotonin neurons.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2009
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Extrasynaptic vesicular transmitter release from the somata of substantia nigra neurons in rat midbrain slices.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1998
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: an investigation of extrasynaptic transmission.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1998
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

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