Extrasynaptic and synaptic NMDA receptors form stable and uniform pools in rat hippocampal slices.

Abstract

N-methyl-d-aspartate receptor (NMDAR) activation can trigger both long- and short-term plasticity, promote cell survival, and initiate cell death. A number of studies suggest that the consequences of NMDAR activation can vary widely depending on whether synaptic or extrasynaptic receptors are activated. Here we have examined the spatial distribution of… (More)

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