Extraordinary neoteny of synaptic spines in the human prefrontal cortex.


The major mechanism for generating diversity of neuronal connections beyond their genetic determination is the activity-dependent stabilization and selective elimination of the initially overproduced synapses [Changeux JP, Danchin A (1976) Nature 264:705-712]. The largest number of supranumerary synapses has been recorded in the cerebral cortex of human and… (More)
DOI: 10.1073/pnas.1105108108


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@article{Petanjek2011ExtraordinaryNO, title={Extraordinary neoteny of synaptic spines in the human prefrontal cortex.}, author={Zdravko Petanjek and Milo{\vs} Juda{\vs} and Goran Simic and Mladen Roko Rasin and H. B. M. Uylings and Pasko Raki{\'c} and Ivica Kostovi{\'c}}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2011}, volume={108 32}, pages={13281-6} }