Extraordinary neoteny of synaptic spines in the human prefrontal cortex.


The major mechanism for generating diversity of neuronal connections beyond their genetic determination is the activity-dependent stabilization and selective elimination of the initially overproduced synapses [Changeux JP, Danchin A (1976) Nature 264:705-712]. The largest number of supranumerary synapses has been recorded in the cerebral cortex of human and… (More)
DOI: 10.1073/pnas.1105108108


2 Figures and Tables

Blog articles referencing this paper

Slides referencing similar topics