Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu

  title={Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu},
  author={Kui Han and Zhi-feng Li and Ran Peng and Li-Ping Zhu and Tao Zhou and Lu-guang Wang and Shu-guang Li and Xiao-bo Zhang and Wei Hu and Zhi-hong Wu and Nan Qin and Yue-Zhong Li},
  booktitle={Scientific reports},
Complex environmental conditions can significantly affect bacterial genome size by unknown mechanisms. The So0157-2 strain of Sorangium cellulosum is an alkaline-adaptive epothilone producer that grows across a wide pH range. Here, we show that the genome of this strain is 14,782,125 base pairs, 1.75-megabases larger than the largest bacterial genome from S. cellulosum reported previously. The total 11,599 coding sequences (CDSs) include massive duplications and horizontally transferred genes… CONTINUE READING
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