Extraordinary conservation, gene loss, and positive selection in the evolution of an ancient neurotoxin.

@article{Murray2011ExtraordinaryCG,
  title={Extraordinary conservation, gene loss, and positive selection in the evolution of an ancient neurotoxin.},
  author={Shauna A. Murray and Troco Kaan Mihali and Brett A Neilan},
  journal={Molecular biology and evolution},
  year={2011},
  volume={28 3},
  pages={1173-82}
}
The recent determination of the genetic basis for the biosynthesis of the neurotoxin, saxitoxin, produced by cyanobacteria, has revealed a highly complex sequence of reactions, involving over 30 biosynthetic steps encoded by up to 26 genes clustered at one genomic locus, sxt. Insights into evolutionary-ecological processes have been found through the study of such secondary metabolites because they consist of a measurable phenotype with clear ecological consequences, synthesized by known genes… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 58 references

Similar Papers

Loading similar papers…