Extranodal Rosai-Dorfman disease in children.

  title={Extranodal Rosai-Dorfman disease in children.},
  author={Carlos Rodriguez-Galindo and Kathleen J. Helton and Niria D S{\'a}nchez and Martha D Rieman and Michael Jeng and Winfred C. Wang},
  journal={Journal of pediatric hematology/oncology},
  volume={26 1},
Sinus histiocytosis with massive lymphadenopathy (SHML), or Rosai-Dorfman disease (RDD), is a histiocytic disorder that usually presents with painless massive cervical lymphadenopathy. The course is usually self-limited, but treatment may be required in cases with compression of vital organs. Patients may present with extranodal involvement only, and in these cases the clinical and histologic diagnosis may be difficult. The authors describe three patients with RDD who had exclusive extranodal… CONTINUE READING

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