Extraneuronal localization of acetylcholine and its release upon nicotinic stimulation in rabbits.

@article{Kawashima1989ExtraneuronalLO,
  title={Extraneuronal localization of acetylcholine and its release upon nicotinic stimulation in rabbits.},
  author={Koichiro Kawashima and Hiroyuki Oohata and Kazuma Fujimoto and Tadahiko Suzuki},
  journal={Neuroscience letters},
  year={1989},
  volume={104 3},
  pages={336-9}
}
A study was undertaken to examine the origin of plasma acetylcholine (ACh). The ACh content of blood cells was about 25 times higher than that of plasma in normal rabbits (3,722 vs 140 pg/ml blood, n = 7). Plasma ACh content in rabbits having antibody against ACh was about 80 times higher than in normal rabbits, while no difference was observed in the ACh content of blood cells between the groups. Nicotine (100 micrograms/kg, i.v.) produced a significant increase in plasma ACh content and a… CONTINUE READING

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