Extragenic suppression of temperature-sensitive phenotype in reovirus: mapping suppressor mutations.

Abstract

Independently isolated, spontaneous pseudorevertants of temperature-sensitive (ts) mutants of reovirus type 3 have previously been genetically characterized (R. F. Ramig and B. N. Fields, 1979, Virology 92, 155-167). Eighteen of these pseudorevertants were backcrossed to wild-type reovirus type 1 and reassortant progeny expressing the parental ts phenotype… (More)

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