Extradural opioids for postoperative analgesia. A double-blind comparison of pethidine, fentanyl and morphine.

Abstract

Pethidine 50 mg, fentanyl 100 microgram and morphine 2 mg administered to the extradural space, were compared in the treatment of pain following surgery. All three drugs produced a rapid decrease in pain scores as assessed using a visual linear analogue, morphine being the least effective. Fentanyl had a relatively short duration of action (2 h), whereas… (More)

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@article{Rutter1981ExtraduralOF, title={Extradural opioids for postoperative analgesia. A double-blind comparison of pethidine, fentanyl and morphine.}, author={Derek Rutter and D G Skewes and Margaret E. Morgan}, journal={British journal of anaesthesia}, year={1981}, volume={53 9}, pages={915-20} }