Extradural analgesia in obstetrics: a controlled trial of carbonated lignocaine and bupivacaine hydrochloride with or without adrenaline.

@article{Moir1976ExtraduralAI,
  title={Extradural analgesia in obstetrics: a controlled trial of carbonated lignocaine and bupivacaine hydrochloride with or without adrenaline.},
  author={Donald Dundas Moir and P. J. Slater and Jennifer Thorburn and R G McLaren and John E. Moodie},
  journal={British journal of anaesthesia},
  year={1976},
  volume={48 2},
  pages={
          129-35
        }
}
Four local anaesthetic solutions (2% carbonated lignocaine with or without adrenaline and 0.5% bupivacaine HCl with or without adrenaline) were used randomly for 335 continuous lumbar extradural blocks in labour. Carbonated lignocaine caused a more rapid onset of analgesia than bupivacaine HCl. The addition of adrenaline made little difference to the onset times, prolonged markedly the duration of analgesia with carbonated lignocaine and had little effect on the duration of analgesia with… 

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