Extracts of Devil's Club (Oplopanax horridus) Exert Therapeutic Efficacy in Experimental Models of Acute Myeloid Leukemia

@article{Mcgill2014ExtractsOD,
  title={Extracts of Devil's Club (Oplopanax horridus) Exert Therapeutic Efficacy in Experimental Models of Acute Myeloid Leukemia},
  author={Colin M. Mcgill and Estefania J Alba-Rodriguez and Shuo Li and Charles Benson and Regina M Ondrasik and Lindsey N. Fisher and David F. Claxton and Brian M Barth},
  journal={Phytotherapy Research},
  year={2014},
  volume={28},
  pages={1308 - 1314}
}
Acute myeloid leukemia (AML) is a group of hematological malignancies defined by expanded clonal populations of immature progenitors (blasts) of myeloid phenotype in blood and bone marrow. Given a typical poor prognostic outlook, there is great need for novel agents with anti‐AML activity. Devil's club (Oplopanax horridus) is one of the most significant medicinal plants used among the indigenous people of Southeast Alaska and the coastal Pacific Northwest, with different linguistic groups… 
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