Extracting Knowledge from Failed Development Programmes

  title={Extracting Knowledge from Failed Development Programmes},
  author={Yaning Wang},
  journal={Pharmaceutical Medicine},
  • Yaning Wang
  • Published 2012
  • Medicine
  • Pharmaceutical Medicine
Drug development is a challenging business with high risks. Multiple factors can contribute to the failure of a programme. Lack of efficacy and unacceptable safety have been the major reasons for product failure since 2000. Even though the drug molecule and disease target are the most fundamental aspects for successful drug development, rational dose and dosing regimen selection also play an important role in the new drug development era and may determine the fate of a programme. Two case… Expand
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