Extracting β-amyloid from Alzheimer's disease.

@article{Dries2012ExtractingF,
  title={Extracting β-amyloid from Alzheimer's disease.},
  author={Daniel R Dries and Gang Yu and Joachim Herz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 9},
  pages={
          3199-200
        }
}
  • Daniel R Dries, Gang Yu, Joachim Herz
  • Published in
    Proceedings of the National…
    2012
  • Biology, Medicine
  • The amyloid hypothesis of Alzheimer's disease (AD) posits that extracellular plaques comprised of the β-amyloid (Aβ) peptide are a root cause of neuronal loss in AD (1). To date, three therapeutic strategies targeting Aβ have been used: (i) inhibiting the production of Aβ, (ii) inhibiting the oligomerization of Aβ, and (iii) promoting the clearance and/or degradation of Aβ. None have led to a therapeutic or preventive medication for AD. As an alternative approach, natural compounds have… CONTINUE READING

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