Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo.

@article{Komutarin2004ExtractOT,
  title={Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo.},
  author={T Komutarin and Shahla Azadi and Leon F Butterworth and Deborah Keil and Benjamart Chitsomboon and Maitree Suttajit and Barbara Jean Meade},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2004},
  volume={42 4},
  pages={649-58}
}
The seed coat extract of Tamarindus indica, a polyphenolic flavonoid, has been shown to have antioxidant properties. The present studies investigated the inhibitory effect of the seed coat extract of T. indica on nitric oxide production in vitro using a murine macrophage-like cell line, RAW 264.7, and in vitro and in vivo using freshly isolated B6C3F1 mouse peritoneal macrophages. In vitro exposure of RAW 264.7 cells or peritoneal macrophages to 0.2-200 microg/mL of T. indica extract… CONTINUE READING

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