Extracorporeal photochemotherapy for treatment of acute and chronic GVHD in childhood.

  title={Extracorporeal photochemotherapy for treatment of acute and chronic GVHD in childhood.},
  author={Laura Salvaneschi and Cesare Perotti and Marco Zecca and Stefano Bernuzzi and Gianluca Viarengo and Giovanna Giorgiani and Claudia Del Fante and Paola Bergamaschi and Rita Maccario and Andrea Pession and Franco Locatelli},
  volume={41 10},
BACKGROUND Extracorporeal photochemotherapy (EPC) has recently been proposed for the treatment of adults with either acute or chronic GVHD. However, data on children given this therapy are scarce. A Phase I-II study was carried out on EPC in children experiencing GVHD after allogeneic transplantation of HPCs. STUDY DESIGN AND METHODS Nine patients with steroid-resistant, grade II-IV acute GVHD and 14 with chronic GVHD, all of whom had been refractory to at least one line of treatment, were… CONTINUE READING


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